| # | Player Name | Date of Birth | Nationality | Apps | Start | Sub | Bench | Goals | Yellow | Red |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | VAN DER SAR Edwin | 29/10/1970 | Dutch | 32 | 32 | 0 | 3 | 0 | 1 | 0 |
| 2 | NEVILLE Gary | 18/02/1975 | English | 24 | 24 | 0 | 0 | 0 | 2 | 0 |
| 3 | EVRA Patrice | 15/05/1981 | French | 24 | 22 | 2 | 5 | 1 | 4 | 0 |
| 4 | HEINZE Gabriel | 19/04/1978 | Argentinean | 22 | 17 | 5 | 2 | 0 | 5 | 0 |
| 5 | FERDINAND Rio | 07/11/1978 | English | 33 | 33 | 0 | 1 | 1 | 3 | 0 |
| 6 | BROWN Wes | 13/10/1979 | English | 22 | 17 | 5 | 8 | 0 | 3 | 0 |
| 7 | RONALDO Cristiano | 05/02/1985 | Portuguese | 34 | 31 | 3 | 1 | 17 | 2 | 0 |
| 8 | ROONEY Wayne | 24/10/1985 | English | 35 | 33 | 2 | 0 | 14 | 5 | 0 |
| 9 | SAHA Louis | 08/08/1978 | French | 24 | 18 | 6 | 4 | 8 | 1 | 0 |
| 11 | GIGGS Ryan | 29/11/1973 | Welsh | 30 | 25 | 5 | 1 | 4 | 5 | 0 |
| 13 | Ji-Sung PARK | 25/02/1981 | South Korean | 14 | 8 | 6 | 2 | 4 | 0 | 0 |
| 14 | SMITH Alan | 28/10/1980 | English | 9 | 6 | 3 | 1 | 0 | 1 | 0 |
| 15 | VIDIC Nemanja | 21/10/1981 | Serbian | 25 | 25 | 0 | 2 | 3 | 7 | 0 |
| 16 | CARRICK Michael | 28/07/1981 | English | 33 | 29 | 4 | 1 | 3 | 2 | 0 |
| 17 | LARSSON Henrik | 10/09/1971 | Swedish | 7 | 5 | 2 | 0 | 1 | 1 | 0 |
| 18 | SCHOLES Paul | 16/11/1974 | English | 30 | 29 | 1 | 2 | 6 | 8 | 1 |
| 19 | ROSSI Giuseppe | 01/02/1987 | Italian | 0 | 0 | 0 | 2 | 0 | 0 | 0 |
| 20 | SOLSKJAER Ole Gunnar | 26/02/1973 | Norwegian | 19 | 9 | 10 | 5 | 7 | 1 | 0 |
| 21 | DONG Fangzhou | 23/01/1985 | Chinese | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| 22 | O'SHEA John | 30/04/1981 | Irish | 32 | 16 | 16 | 4 | 4 | 2 | 0 |
| 23 | RICHARDSON Kieran | 21/10/1984 | English | 15 | 8 | 7 | 4 | 1 | 4 | 0 |
| 24 | FLETCHER Darren | 01/02/1984 | Scottish | 24 | 16 | 8 | 4 | 4 | 0 | 0 |
| 25 | JONES David | 04/11/1984 | English | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 27 | SILVESTRE Mikael | 09/08/1977 | French | 14 | 6 | 8 | 5 | 1 | 0 | 0 |
| 29 | KUSZCZAK Tomasz | 20/03/1982 | Polish | 6 | 6 | 0 | 31 | 0 | 0 | 0 |
| 32 | CATHCART Craig | 06/02/1989 | Irish | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 33 | EAGLES Chris | 19/11/1985 | English | 2 | 1 | 1 | 1 | 1 | 1 | 0 |
| 35 | LEE Kieran | 22/06/1988 | English | 1 | 1 | 0 | 1 | 0 | 1 | 0 |
| 38 | HEATON Thomas | 15/04/1986 | English | 0 | 0 | 0 | 4 | 0 | 0 | 0 |
| Own Goals | 3 | |||||||||
| Totals | 512 | 418 | 94 | 96 | 83 | 59 | 1 | |||