| # | Player Name | Date of Birth | Nationality | Apps | Start | Sub | Bench | Goals | Yellow | Red |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | HOWARD Tim | 06/03/1979 | American | 1 | 0 | 1 | 36 | 0 | 0 | 0 |
| 2 | NEVILLE Gary | 18/02/1975 | English | 25 | 24 | 1 | 0 | 0 | 3 | 0 |
| 3 | EVRA Patrice | 15/05/1981 | French | 11 | 7 | 4 | 5 | 0 | 1 | 0 |
| 4 | HEINZE Gabriel | 19/04/1978 | Argentinean | 4 | 2 | 2 | 2 | 0 | 0 | 0 |
| 5 | FERDINAND Rio | 07/11/1978 | English | 37 | 37 | 0 | 0 | 3 | 1 | 1 |
| 6 | BROWN Wes | 13/10/1979 | English | 19 | 17 | 2 | 5 | 0 | 3 | 0 |
| 7 | RONALDO Cristiano | 05/02/1985 | Portuguese | 33 | 24 | 9 | 1 | 9 | 8 | 1 |
| 8 | ROONEY Wayne | 24/10/1985 | English | 36 | 34 | 2 | 0 | 16 | 8 | 0 |
| 9 | SAHA Louis | 08/08/1978 | French | 19 | 12 | 7 | 4 | 7 | 0 | 0 |
| 10 | VAN NISTELROOY Ruud | 01/07/1976 | Dutch | 35 | 28 | 7 | 1 | 21 | 5 | 0 |
| 11 | GIGGS Ryan | 29/11/1973 | Welsh | 27 | 22 | 5 | 1 | 2 | 3 | 0 |
| 13 | Ji-Sung PARK | 25/02/1981 | South Korean | 33 | 23 | 10 | 1 | 2 | 0 | 0 |
| 14 | SMITH Alan | 28/10/1980 | English | 21 | 15 | 6 | 0 | 1 | 4 | 0 |
| 15 | VIDIC Nemanja | 21/10/1981 | Serbian | 11 | 9 | 2 | 4 | 0 | 3 | 0 |
| 16 | KEANE Roy | 10/08/1971 | Irish | 5 | 4 | 1 | 0 | 0 | 1 | 0 |
| 17 | MILLER Liam | 13/02/1981 | Irish | 1 | 0 | 1 | 2 | 0 | 0 | 0 |
| 18 | SCHOLES Paul | 16/11/1974 | English | 20 | 18 | 2 | 0 | 2 | 3 | 0 |
| 19 | VAN DER SAR Edwin | 29/10/1970 | Dutch | 38 | 38 | 0 | 0 | 0 | 0 | 0 |
| 20 | SOLSKJAER Ole Gunnar | 26/02/1973 | Norwegian | 3 | 0 | 3 | 0 | 0 | 0 | 0 |
| 22 | O'SHEA John | 30/04/1981 | Irish | 34 | 34 | 0 | 0 | 1 | 5 | 0 |
| 23 | RICHARDSON Kieran | 21/10/1984 | English | 22 | 12 | 10 | 4 | 1 | 4 | 0 |
| 24 | FLETCHER Darren | 01/02/1984 | Scottish | 27 | 23 | 4 | 4 | 1 | 3 | 0 |
| 25 | FORTUNE Quinton | 21/05/1977 | South African | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 26 | BARDSLEY Phillip | 28/06/1985 | English | 8 | 3 | 5 | 7 | 0 | 1 | 0 |
| 27 | SILVESTRE Mikael | 09/08/1977 | French | 33 | 30 | 3 | 1 | 1 | 4 | 0 |
| 28 | PIQUE Gerard | 02/02/1987 | Spanish | 3 | 1 | 2 | 7 | 0 | 0 | 0 |
| 30 | STEELE Luke | 24/09/1984 | English | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 31 | JONES David | 04/11/1984 | English | 0 | 0 | 0 | 1 | 0 | 0 | 0 |
| 42 | ROSSI Giuseppe | 01/02/1987 | Italian | 5 | 1 | 4 | 9 | 1 | 0 | 0 |
| Own Goals | 4 | |||||||||
| Totals | 511 | 418 | 93 | 97 | 72 | 60 | 2 | |||